虚血チームの臨床研究

現在進行している自主臨床試験

P2009032-11X 冠動脈疾患患者に対するピタバスタチンによる積極的脂質低下療法または通常脂質低下療法のランダム化比較試験 (REAL-CAD)

P2010002-11X 糖尿病網膜症合併高コレステロール血症患者を対象としたスタチンによるLDL-C低下療法 (通常治療/強化治療) の比較研究

P2010038-11X 心筋梗塞既往歴のある高血圧患者におけるアリスキレンの心筋血流予備能及び冠血流予備能に及ぼす影響に関する、非盲検、ランダム化、並行群間比較試験

P2011024-11X 冠動脈疾患を発症した2型糖尿病患者におけるDPP-4阻害薬投与群および従来糖尿病療法群のIVUSとFFRを指標とした冠動脈プラーク・血流への影響に関する前向き無作為比較試験

P2011033-11Y リアルワールドの日本人患者におけるEndeavor ZESを用いる治療後のDAPTの至適実施期間の検討:前向き多施設共同治験(OPERA Study)

P2012032-11Y 冠動脈分岐部ステントの多施設共同比較試験
Bifurcation stEntinG using 2lInk stent:Nobori vs 3link steNt:Xience/PROMUS (BEGIN)

発表論文

Hasumi E, Iwata H, Kohro T, Manabe I, Kinugawa K, Morisaki N, Ando J, Sawaki D, Takahashi M, Fujita H, Yamashita H, Ako J, Hirata Y, Komuro I, Nagai R. Diagnostic implication of change in b-type natriuretic peptide (BNP) for prediction of subsequent target lesion revascularization following silorimus-eluting stent deployment. Int J Cardiol. 2013 Jan 7. pii: S0167-5273(12)01675-0.

Soma K, Takahashi M, Sato T, Nagai R. Angina as a manifestation of constrictive pericarditis. Intern Med. 2012;51(14):1939.

Myojo M, Iwata H, Kohro T, Sato H, Kiyosue A, Ando J, Sawaki D, Takahashi M, Fujita H, Hirata Y, Nagai R. Prognostic implication of macrocytosis on adverse outcomes after coronary intervention. Atherosclerosis. 2012 Mar;221(1):148-53.

Fujita H, Nagai R. Glycemic control is another target of PCI in diabetic patients--to improve clinical outcome from outside the procedure. Circ J. 2011;75(4):773-4.

Kiyosue A, Nagata D, Myojo M, Sato T, Takahashi M, Satonaka H, Nagai R, Hirata Y. Aldosterone-induced osteopontin gene transcription in vascular smooth muscle cells involves glucocorticoid response element. Hypertens Res. 2011 Dec;34(12):1283-7.

Hasumi E, Iwata H, Saito K, Fujiu K, Ando J, Imai Y, Fujita H, Hirata Y, Nagai R. Diagnostic efficacy of coronary CT angiography as a follow-up modality for procedure-related coronary dissection. Int Heart J. 2011;52(4):240-2.

Takahashi M, Shimizu T, Inajima T, Hosoya Y, Takeda N, Ishizaka N, Yamashita H, Hirata Y, Nagai R. A case of localized IgG4-related thoracic periarteritis and recurrent nerve palsy. Am J Med Sci. 2011 Feb;341(2):166-9.

Kiyosue A, Hirata Y, Ando J, Fujita H, Morita T, Takahashi M, Nagata D, Kohro T, Imai Y, Nagai R. Plasma cystatin C concentration reflects the severity of coronary artery disease in patients without chronic kidney disease. Circ J. 2010 Nov;74(11):2441-7.

Kiyosue A, Hirata Y, Ando J, Fujita H, Morita T, Takahashi M, Nagata D, Kohro T, Imai Y, Nagai R. Relationship between renal dysfunction and severity of coronary artery disease in Japanese patients. Circ J. 2010 Apr;74(4):786-91.

Higashikuni Y, Nagashima T, Ishizaka N, Kinugawa K, Hirata Y, Nagai R. Right aortic arch with mirror image branching and vascular ring. Int J Cardiol. 2008 Oct 30;130(1):e53-5.

Higashikuni Y, Ishizaka N, Ishizaka Y, Toda E, Nagai R, Yamakado M. Relationship between blood pressure and chronic kidney disease in the Japanese population: the lower the better even in individuals without hypertension Hypertens Res. 2008 Feb;31(2):213-9.

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