研究実績(2022年)

英文論文(2022年)

Yamada S, Ko T, Hatsuse S, Nomura S, Zhang B, Dai Z, Inoue S, Kubota M, Sawami K, Yamada T, Sassa T, Katagiri M, Fujita K, Katoh M, Ito M, Harada M, Toko H, Takeda N, Morita H, Aburatani H, Komuro I.
Spatiotemporal transcriptome analysis reveals critical roles for mechano-sensing genes at the border zone in remodeling after myocardial infarction.
Nat Cardiovasc Res 2022 Nov;1:1072-83 
Kiriyama H, Kiyosue A, Minatsuki S, Kawahara T, Katsushika S, Kamon T, Hirose K, Shinohara H, Miura M, Saito A, Kikuchi H, Kodera S, Hatano M, Ando J, Myojo M, Itoh N, Yamamoto K, Ikenouchi H, Takeda N, Komuro I.
Potential value of saline-induced Pd/Pa ratio in patients with coronary artery stenosis.
Front Cardiovasc Med 2022;9:1001833
Yamamoto Y, Daimon M, Nakanishi K, Nakao T, Hirokawa M, Ishiwata J, Kiriyama H, Yoshida Y, Iwama K, Hirose K, Mukai Y, Takeda N, Yatomi Y, Komuro I.
Incidence of atrial functional tricuspid regurgitation and its correlation with tricuspid valvular deformation in patients with persistent atrial fibrillation.
Front Cardiovasc Med 2022;9:1023732
Ieki H, Ito K, Saji M, Kawakami R, Nagatomo Y, Takada K, Kariyasu T, Machida H, Koyama S, Yoshida H, Kurosawa R, Matsunaga H, Miyazawa K, Ozaki K, Onouchi Y, Katsushika S, Matsuoka R, Shinohara H, Yamaguchi T, Kodera S, Higashikuni Y, Fujiu K, Akazawa H, Iguchi N, Isobe M, Yoshikawa T, Komuro I.
Deep learning-based age estimation from chest X-rays indicates cardiovascular prognosis.
Commun Med (Lond) 2022 Dec 9;2:159
Yoshida Y, Nakanishi K, Daimon M, Hirose K, Ishiwata J, Kaneko H, Nakao T, Mizuno Y, Morita H, Di Tullio MR, Homma S, Komuro I.
Aortic valve sclerosis and subclinical LV dysfunction in the general population with normal LV geometry.
Eur J Prev Cardiol 2022 Nov 22
Nakamura S, Numata G, Yamaguchi T, Tokiwa H, Higashikuni Y, Nomura S, Sasano T, Takimoto E, Komuro I.
Endoplasmic reticulum stress-activated nuclear factor-kappa B signaling pathway induces the upregulation of cardiomyocyte dopamine D1 receptor in heart failure.
Biochem Biophys Res Commun 2022 Dec 31;637:247-53
Katagiri M, Yamada S, Katoh M, Ko T, Ito M, Komuro I.
Heart Failure Pathogenesis Elucidation and New Treatment Method Development.
JMA J 2022 Oct 17;5:399-406
Sawano S, Kodera S, Sato M, Katsushika S, Sukeda I, Takeuchi H, Shinohara H, Kobayashi A, Takiguchi H, Hirose K, Kamon T, Saito A, Kiriyama H, Miura M, Minatsuki S, Kikuchi H, Higashikuni Y, Takeda N, Fujiu K, Ando J, Akazawa H, Morita H, Komuro I.
Age prediction from coronary angiography using a deep neural network: Age as a potential label to extract prognosis-related imaging features.
PLoS One 2022;17:e0276928
Isotani Y, Amiya E, Ishida J, Komuro I.
Summation of Precordial R Wave Amplitudes, a Clinical Parameter for Detecting Early TTR Amyloidosis Cardiac Involvement.
J Cardiovasc Dev Dis 2022 Oct 11;9
Ko T, Morita H.
Molecular Genomic Autopsy - Clues to Preventing Further Tragedy?
Circ J 2022 Dec 23;87:120-22
Kaneko H, Yano Y, Lee H, Lee HH, Okada A, Suzuki Y, Itoh H, Matsuoka S, Fujiu K, Michihata N, Jo T, Takeda N, Morita H, Nishiyama A, Node K, Kim HC, Yasunaga H, Komuro I.
Blood Pressure Classification Using the 2017 ACC/AHA Guideline and Heart Failure in Patients With Cancer.
J Clin Oncol 2023 Feb 10;41:980-90 
Adachi Y, Ueda K, Nomura S, Ito K, Katoh M, Katagiri M, Yamada S, Hashimoto M, Zhai B, Numata G, Otani A, Hinata M, Hiraike Y, Waki H, Takeda N, Morita H, Ushiku T, Yamauchi T, Takimoto E, Komuro I.
Beiging of perivascular adipose tissue regulates its inflammation and vascular remodeling.
Nat Commun 2022 Sep 7;13:5117 
Kodera S, Morita H, Nishi H, Takeda N, Ando J, Komuro I.
Cost-Effectiveness of Dapagliflozin for Chronic Kidney Disease in Japan.
Circ J 2022 Nov 25;86:2021-28
Bujo S, Amiya E, Maeda MH, Ishida J, Hatano M, Ishizuka M, Uehara M, Oshima T, Kojima T, Nakanishi K, Daimon M, Shimizu J, Toda T, Komuro I.
The effect of immunosuppressive therapy on cardiac involvements in anti-mitochondrial antibody-positive myositis.
ESC Heart Fail 2022 Dec;9:4112-19
Kaneko H, Suzuki Y, Ueno K, Okada A, Fujiu K, Matsuoka S, Michihata N, Jo T, Takeda N, Morita H, Kamiya K, Node K, Yasunaga H, Komuro I.
Association of Life’s Simple 7 with incident cardiovascular disease in 53 974 patients with cancer.
Eur J Prev Cardiol 2022 Dec 21;29:2324-32
Kaneko H, Yano Y, Suzuki Y, Okada A, Itoh H, Matsuoka S, Fujiu K, Michihata N, Jo T, Takeda N, Morita H, Node K, Viera AJ, Lima JAC, Oparil S, Lam CSP, Carey RM, Yasunaga H, Komuro I.
Reduction in blood pressure for elevated blood pressure/stage 1 hypertension according to the American College of Cardiology/American Heart Association guideline and cardiovascular outcomes.
Eur J Prev Cardiol 2022 Oct 20;29:1921-29
Ishizuka M, Uehara M, Katagiri M, Ishida J, Kojima T, Amiya E, Komuro I.
Successful treatment of recurrent cardiac sarcoidosis with the combination of corticosteroid and methotrexate monitored by (18)F-fluoro-2-deoxyglucose positron emission tomography: case series.
Eur Heart J Case Rep 2022 Aug;6:ytac334
Yao A, Inuzuka R, Mizuno A, Iwano H, Tatebe S, Tsukamoto Y, Sakamoto I, Watanabe H, Fukuda N, Takechi F, Adachi S, Akazawa Y, Kuwahara K, Dohi K, Ishizu T, Miyake M, Koitabashi N, Hasegawa-Tamba S, Sato S, Fujii T, Ehara E, Minamino T, Yamada H, Yamashita E, Kawamatsu N, Masuda K, Soma K, Shiraishi I, Nagai R, Niwa K.
Status of adult outpatients with congenital heart disease in Japan: The Japanese Network of Cardiovascular Departments for Adult Congenital Heart Disease Registry.
J Cardiol 2022 Dec;80:525-31
Mukai Y, Nakanishi K, Daimon M, Sawada N, Hirose K, Iwama K, Yamamoto Y, Yoshida Y, Ishiwata J, Koyama K, Nakao T, Morita H, Di Tullio MR, Homma S, Komuro I.
Association of arterial properties with left ventricular morphology and function in the community.
J Hypertens 2022 Dec 1;40:2423-29
Numata G, Takimoto E, Kariya T, Adachi Y, Tokiwa H, Toyoda M, Mafune R, Saito Y, Nakamura S, Ueda K, Ikeda Y, Komuro I.
A pacing-controlled protocol for frequency-diastolic relations distinguishes diastolic dysfunction specific to a mouse HFpEF model.
Am J Physiol Heart Circ Physiol 2022 Sep 1;323:H523-H27
Yagi H, Takeda N, Hosoya Y, Yamauchi H, Komuro I.
Giant internal carotid artery aneurysms and porcelain aorta in an elderly patient with Marfan syndrome.
Clin Case Rep 2022 Aug;10:e6190
Kakuda N, Nakayama A, Ishizuka M, Takeda N, Morita H, Itoda Y, Ono M, Komuro I.
Delayed diagnosis of severe traumatic tricuspid regurgitation after traffic injury.
J Cardiol Cases 2022 Apr;25:204-06
Ko T, Morita H.
Takotsubo Cardiomyopathy and Peripartum Cardiomyopathy.
Int Heart J 2022;63:651-53
Amiya E, Morita H.
Simple Way of Identifying High-Risk Group of Heart Failure in Hypertrophic Cardiomyopathy in the Japanese Population.
Circ J 2022 Nov 25;86:1941-42
Itoh H, Kaneko H, Okada A, Suzuki Y, Fujiu K, Matsuoka S, Michihata N, Jo T, Nakanishi K, Takeda N, Morita H, Node K, Di Tullio MR, Homma S, Yasunaga H, Komuro I.
Age-Specific Relation of Cardiovascular Health Metrics With Incident Cardiovascular Disease.
Am J Cardiol 2022 Aug 15;177:34-39
Goto K, Nakayama Y, Saito A, Minatsuki S, Takeda N, Akamatsu N, Hatano M, Komuro I.
Middle-Aged Case of Congenital Portosystemic Venous Shunt Complicated With Multiple Visceral Arterial Aneurysms and Aorto-Pulmonary Collateral Vessels.
Circ Cardiovasc Imaging 2022 Jul;15:e013969
Kakuda N, Amiya E, Hatano M, Tsuji M, Bujo C, Ishida J, Yagi H, Saito A, Narita K, Isotani Y, Fujita K, Ando M, Shimada S, Kinoshita O, Ono M, Komuro I.
Residual Pulmonary Vascular Resistance Increase Under Left Ventricular Assist Device Support Predicts Long-Term Cardiac Function After Heart Transplantation.
Front Cardiovasc Med 2022;9:904350
Ko T, Nomura S, Yamada S, Fujita K, Fujita T, Satoh M, Oka C, Katoh M, Ito M, Katagiri M, Sassa T, Zhang B, Hatsuse S, Yamada T, Harada M, Toko H, Amiya E, Hatano M, Kinoshita O, Nawata K, Abe H, Ushiku T, Ono M, Ikeuchi M, Morita H, Aburatani H, Komuro I.
Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-beta-IGFBP7 axis.
Nat Commun 2022 Jun 7;13:3275 
Matsubara TJ, Fujiu K, Kodera S, Kani K, Goto K, Shimizu Y, Oguri G, Hasumi E, Kojima T, Komuro I.
Prediction of Atrial Fibrillation Being Asymptomatic at First Onset by Cardiac Pacing.
Int Heart J 2022;63:486-91
Nakanishi K, Morita H.
Uric Acid.
Int Heart J 2022;63:423-25
Narita K, Amiya E, Hatano M, Ishida J, Minatsuki S, Tsuji M, Bujo C, Kakuda N, Isotani Y, Ono M, Komuro I.
Determining the factors for interhospital transfer in advanced heart failure cases.
Int J Cardiol Heart Vasc 2022 Jun;40:101035
Yamamoto Y, Kiriyama H, Daimon M, Mori Y, Yamauchi H, Miura M, Komuro I.
Esophageal hematoma associated with transesophageal echocardiography during transcatheter aortic valve replacement in an elderly Japanese woman.
J Med Ultrason (2001) 2022 Jul;49:481-83
Yagi H, Takeda N, Amiya E, Akiyama N, Chang H, Ishiura H, Sato J, Akazawa H, Morita H, Komuro I.
Nonsyndromic arteriopathy and aortopathy and vascular Ehlers-Danlos syndrome causing COL3A1 variants.
Am J Med Genet A 2022 Sep;188:2777-82
Kaneko H, Yano Y, Lee HH, Lee H, Okada A, Itoh H, Morita K, Fukui A, Fujiu K, Suzuki Y, Matsuoka S, Nakamura S, Michihata N, Jo T, Takeda N, Morita H, Yokoo T, Nishiyama A, Node K, Viera AJ, Muntner P, Oparil S, Kim HC, Yasunaga H, Komuro I.
Medication-Naive Blood Pressure and Incident Cancers: Analysis of 2 Nationwide Population-Based Databases.
Am J Hypertens 2022 Aug 1;35:731-39
Numata G, Takimoto E.
Cyclic GMP and PKG Signaling in Heart Failure.
Front Pharmacol 2022;13:792798
Shimbo M, Hatano M, Ishii S, Saito A, Yagi H, Minatsuki S, Maki H, Amiya E, Takeda N, Komuro I.
Renal replacement therapy as a therapeutic option for right heart failure in severe pulmonary arterial hypertension.
ESC Heart Fail 2022 Aug;9:2728-31
Matsuoka S, Kaneko H, Okada A, Fukui A, Yano Y, Itoh H, Morita K, Fujiu K, Michihata N, Jo T, Takeda N, Morita H, Yamaguchi S, Nakamura S, Nishiyama A, Yokoo T, Node K, Yamauchi T, Nangaku M, Yasunaga H, Komuro I.
Association between proteinuria and incident colorectal cancer: analysis of a nationwide population-based database.
BMJ Open 2022 Apr 4;12:e056250
Nomura S, Morita H.
Dysregulation of DNA Methylation in the Aryl-Hydrocarbon Receptor Repressor (AHRR) Gene.
Circ J 2022 May 25;86:993-94
Liu W, Higashikuni Y, Sata M.
Linking RNA dynamics to heart disease: the lncRNA/miRNA/mRNA axis in myocardial ischemia-reperfusion injury.
Hypertens Res 2022 Jun;45:1067-69
Nakayama A, Kodera S, Morita H, Fujiwara T, Takeda N, Komuro I.
Cost-Effectiveness of Management for Hospitalized Patients.
Int Heart J 2022;63:264-70
Amiya E.
Social Inequalities in Non-ischemic Cardiomyopathies.
Front Cardiovasc Med 2022;9:831918
Morita H, Komuro I.
AQP1 Promoter Variant, Water Transport, and Outcome in Peritoneal Dialysis.
N Engl J Med 2022 Mar 17;386:1096-98
Matsuoka S, Kaneko H, Okada A, Itoh H, Suzuki Y, Fujiu K, Michihata N, Jo T, Takeda N, Morita H, Nakamura S, Node K, Yasunaga H, Komuro I.
Association of retinal atherosclerosis assessed using Keith-Wagener-Barker system with incident heart failure and other atherosclerotic cardiovascular disease: Analysis of 319,501 individuals from the general population.
Atherosclerosis 2022 May;348:68-74
Kadowaki H, Akazawa H.
Sick Sinus Syndrome: More Than a Needle-in-a-haystack Manifestation of Immune Checkpoint Inhibitor-associated Myocarditis.
Intern Med 2022 Jul 15;61:2101-02
Nakanishi K, Daimon M, Yoshida Y, Ishiwata J, Sawada N, Hirokawa M, Kaneko H, Nakao T, Mizuno Y, Morita H, Di Tullio MR, Homma S, Komuro I.
Blood pressure categorization and subclinical left ventricular dysfunction in antihypertensive medication-naive subjects.
ESC Heart Fail 2022 Jun;9:1766-74
Isotani Y, Amiya E, Ishida J, Ishizuka M, Hatano M, Nakanishi K, Daimon M, Komuro I.
Recovery of sinus rhythm by tafamidis in patients with wild-type transthyretin amyloid cardiomyopathy with atrial arrhythmias.
Oxf Med Case Reports 2022 Feb;2022:omac007
Umei M, Akazawa H, Saga-Kamo A, Yagi H, Liu Q, Matsuoka R, Kadowaki H, Shindo A, Nakashima A, Yasuda K, Suzuki K, Komuro I.
Oral Administration of Euglena Gracilis Z Alleviates Constipation and Cardiac Dysfunction in a Mouse Model of Isoproterenol-Induced Heart Failure.
Circ Rep 2022 Feb 10;4:83-91
Yagi H, Takiguchi H, Takeda N, Inuzuka R, Taniguchi Y, Porto KJ, Ishiura H, Mitsui J, Morita H, Komuro I.
Family with congenital contractural arachnodactyly due to a novel multiexon deletion of the FBN2 gene.
Clin Case Rep 2022 Feb;10:e05335
Tsuji M, Kakuda N, Bujo C, Ishida J, Amiya E, Hatano M, Shimada A, Imai H, Shimada S, Kinoshita O, Yamauchi H, Ono M, Komuro I.
Sarcopenia and risk of infection in adult heart transplant recipients in Japan.
ESC Heart Fail 2022 Apr;9:1413-23
Goto K, Minatsuki S, Fujita K, Takeda N, Hatano M, Komuro I.
Two Siblings With Peripheral Pulmonary Arterial Stenosis: Pulmonary Angiography of Advanced and Early Stages.
Chest 2022 Feb;161:e75-e80
Goto K, Shimizu Y, Kojima T, Takeda N, Fujiu K, Komuro I.
Cholecystitis and Cholangitis during Continuous Renal Replacement Therapy in a Patient with Retroperitoneal Hemorrhage Requiring Large Amounts of Contrast Medium for the Assessment and Intervention.
Intern Med 2022 Aug 15;61:2533-37
Kamon T, Kaneko H, Itoh H, Okada A, Matsuoka S, Kiriyama H, Fujiu K, Morita K, Michihata N, Jo T, Takeda N, Morita H, Nakamura S, Node K, Yasunaga H, Komuro I.
Sex Difference in the Association between Lipid Profile and Incident Cardiovascular Disease among Young Adults.
J Atheroscler Thromb 2022 Oct 1;29:1475-86
Hatano M, Jimba T, Fujiwara T, Tsuji M, Bujo C, Ishida J, Amiya E, Kinoshita O, Ono M.
Late-onset right ventricular failure after continuous-flow left ventricular assist device implantation: case presentation and review of the literature.
J Cardiol 2022 Aug;80:110-15
Matsuoka S, Kaneko H, Okada A, Morita K, Itoh H, Michihata N, Jo T, Takeda N, Morita H, Fujiu K, Nakamura S, Node K, Yasunaga H, Komuro I.
Age Modified Relationship Between Modifiable Risk Factors and the Risk of Atrial Fibrillation.
Circ Arrhythm Electrophysiol 2022 Jan;15:e010409
Kawata T, Daimon M, Nakanishi K, Kimura K, Sawada N, Nakao T, Hirokawa M, Ishiwata J, Takeda N, Yatomi Y, Komuro I.
Factors influencing inferior vena cava diameter and its respiratory variation: Simultaneous comparison with hemodynamic data.
J Cardiol 2022 May;79:642-47
Matsuoka S, Kaneko H, Kamon T, Suzuki Y, Yano Y, Okada A, Itoh H, Morita K, Fukui A, Fujiu K, Michihata N, Jo T, Takeda N, Morita H, Nakamura S, Yokoo T, Nishiyama A, Node K, Yasunaga H, Komuro I.
Incorporation of Retinal Arteriolosclerosis into Risk Stratification of Blood Pressure Category According to the 2017 ACC/AHA Blood Pressure Guideline.
J Atheroscler Thromb 2022 Oct 1;29:1487-98
Higashikuni Y, Liu W, Sata M.
Give a Leg Up: Screening for Peripheral Artery Disease after Acute Myocardial Infarction.
J Atheroscler Thromb 2022 Jul 1;29:989-91
Kodera S, Akazawa H, Morita H, Komuro I.
Prospects for cardiovascular medicine using artificial intelligence.
J Cardiol 2022 Mar;79:319-25
Ando J, Otani K, Redel T, Minatsuki S, Kikuchi H, Kodera S, Komuro I.
Agreement between single plane and biplane derived angiographic fractional flow reserve in patients with intermediate coronary artery stenosis.
Heart Vessels 2022 Apr;37:549-54
Sawano S, Kodera S, Katsushika S, Nakamoto M, Ninomiya K, Shinohara H, Higashikuni Y, Nakanishi K, Nakao T, Seki T, Takeda N, Fujiu K, Daimon M, Akazawa H, Morita H, Komuro I.
Deep learning model to detect significant aortic regurgitation using electrocardiography.
J Cardiol 2022 Mar;79:334-41
Umei M, Saito A, Soma K, Inaba T, Uehara M, Komuro I, Yao A.
Clinical Outcome of Closure of a Small Atrial Septal Defect in a Patient with Pulmonary Arterial Hypertension.
Intern Med 2022 Mar 15;61:851-55
Nakanishi K, Daimon M.
Aging and myocardial strain.
J Med Ultrason (2001) 2022 Jan;49:53-60
Nakayama A, Morita H, Sato T, Kawahara T, Takeda N, Kato S, Itoh H, Komuro I.
Small Dense Low-Density Lipoprotein Cholesterol is a Potential Marker for Predicting Laser Treatment for Retinopathy in Diabetic Patients.
J Atheroscler Thromb 2022 May 1;29:678-91
Narita K, Amiya E.
Social and environmental risks as contributors to the clinical course of heart failure.
Heart Fail Rev 2022 Jul;27:1001-16

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